1
The spectrum of disease includes candidemia and acute and chronic disseminated candidiasis.
2
In disseminated candidiasis, various organs frequently become involved, usually as a consequence of hematogenous spread of the organism.
3
The infant reported here had shown progressive deterioration from disseminated candidiasis until conventional amphotericin B therapy was replaced with A-complex.
4
At seven weeks of age, she developed severe disseminated candidiasis, which failed to respond to conventional amphotericin B and fluconazole therapy.
5
Compared to the parental strain, the homozygous null mutant strain was far less virulent for mice in an intravenous infection model of disseminated candidiasis.
1
One patient died due to systemic candidiasis on day 12 of therapy.
2
Median age at the onset of systemic candidiasis was 17 days.
3
In addition, mice lacking Mincle showed a significantly increased susceptibility to systemic candidiasis.
4
Objective: To report the successful use of amphotericin B lipid complex in treating severe systemic candidiasis in a very-low-birth-weight infant.